What is required for all eligible cancer-related research studies involving human subjects?

Approval from an internal or external Institutional Review Board (IRB) is a critical component for all eligible cancer-related research studies involving human subjects. The primary purpose of an IRB is to protect the rights and welfare of research participants. This body is responsible for ensuring that the proposed studies comply with ethical standards and regulatory requirements, safeguarding participants from potential risks associated with research activities.

The requirement for IRB approval reflects the commitment to ethical research practices and is mandated by federal regulations. All research involving human subjects must undergo this review process to assess factors such as informed consent, risk-benefit analysis, and the overall ethical implications. This is especially vital in cancer research, where the vulnerability of patients and the sensitivity of health data require rigorous oversight.

While there may be other operational processes involved in a research study, such as obtaining funding or institutional certification, those do not replace the paramount need for IRB approval, which is essential for the ethical conduct of research involving human participants.